The course focuses on the application of advanced knowledge of the complex physiological functions and pathophysiological processes to the care of individuals with healthcare problems. Course content examines alterations in function as well as adaptive, integrative and regulatory mechanisms at the molecular, cellular, organ and system levels. The course is designed to enable the graduate nursing student to recognize and analyze these physiological changes and to apply this knowledge in a wide variety of clinical settings. Prerequisites: NRHL 5501, NRHL 5502, NRHL 5505, and NRHL 5506. 3 semester credit hour/s.